Application of second derivative spectrometry to the determination of bromhexine hydrochloride and spectrophotometry to the determination of dyphylline in compound preparation

二阶导数光谱法和紫外光谱法测定复方制剂中盐酸溴己胺和二羟丙茶碱

OBJECTIVE To establish an analytical method for the fast and simultaneous determinations of the three effective components contained in the compound clorprenaline bromhexine capsules .

目的：建立复方氯丙那林溴己新胶囊3种有效成分的快速同时测定方法。实验三观察治疗药物对UC大鼠血清NO含量的影响。

The structure , property , indication , side-effect and clinical evaluation of several bromine-contained medical products are introduced , i.e. bromhexine hydrochloride , ambroxol hydrochloride , benzbromarone and scopolamine butylbromide .

介绍几种含溴药品盐酸溴己新、盐酸氨溴索、苯溴马隆、丁溴东莨菪碱的结构和性质、适应证和副作用以及临床评价。

This paper reports a gas chromatography electron capture detection ( GC ECD ) method for the study of pharmacokinetics of bromhexine in healthy human body A 2 m × 3 mm i.d.

建立了人血浆中溴己新的气相色谱电子捕获测定法，对溴己新胶囊在健康人体内的药代动力学进行了研究。色谱柱为5%SE30（2m×3mmi.d.）

Based on the near infrared fiber diffuse reflectance spectroscopy , the analytical methods of the fast and simultaneous determinations for clorprenaline hydrochloride , bromhexine hydrochloride and decloxizine hydrochloride contained in the compound clorprenaline have been established by the partial least squares method .

本文采用近红外光纤漫发射技术，以偏最小二乘法分别建立了复方氯丙那林胶囊的三种药效成分盐酸氯丙那林、盐酸溴己新和盐酸去氯羟嗪的快速同时测定方法。