Recurrent cases in the ritonavir group plummeted by a highly significant 59 % .

复发病例服用利托那韦组病例减少了59%，具有统计学上高度的显著性意义。

Given that ritonavir blocks cytochrome p450 , a liver enzyme that plays a key role in metabolizing drugs , the researchers wondered whether the drug might have extended lumefantrine 's preventive effects .

由于利托那韦能阻断一种肝脏酶细胞色素p450在药物代谢中发挥的关键作用，研究人员想知道利托那韦是否可能有延长苯芴醇预防疟疾的作用。

If ritonavir " potentiates the long tail of lumefantrine , " he says , " we certainly want to know . "

利托那韦是否“会延长苯芴醇的药效时间，”他说，“我们确实需要了解。”

When it came to first episodes , the group taking ritonavir had a 29 % reduction in malaria cases , which hinted at some effect but was not statistically significant .

疟疾首次发作时，服用利那托韦组的疟疾病例减少了29%，示意此药有一些效果，但没有统计学上的显著意义。

The researchers teased out the effects of ritonavir by separately analyzing first episodes of malaria and recurrent cases .

研究人员通过分别地分析疟疾首发和复发的情况，梳理出利托那韦的效果。