Familial primary erythromelalgia is often inherited in an autosomal dominant manner .

家族性原发性肢端红痛症通常是显性遗传。

Evidences of reduced the sodium channel firing threshold associated with increased frequency of firing electric potentials with a gain of function was reported in the familial erythromelalgia .

证据显示因「功能获得」，在家族性肢端红痛症，钠离子通道产生动作电位有较低的阀值及增加产生动作电位的频率，已经被报告过。