Method 18 patients received only chemotherapy and 16 patients with addition of bonin were compared .

方法应用博宁联合化疗16例与单纯化疗18例进行对照研究。

Objective : to evaluate curative effect of bone metastatic cancer pain by radiotherapy and bonin .

目的：对比观察骨转移癌疼痛行放疗止痛和博宁止痛的疗效。

Conclusion bonin , as a safe and effective bisphosphonates preparation , could relieve bone pain in multiple myeloma more effectively when combined with chemotherapy .

结论博宁是一种安全有效的双膦酸盐制剂，与化疗联合应用可以显著缓解多发性骨髓瘤患者的骨痛。

Conclusion bonin can reduce the cancer related pain developed by bone metastases and its side effects are slight , so patients in poor conditions can receive it .

结论博宁能有效地减轻骨转移引起的疼痛，其毒副反应轻微，一般体质差的病人也能耐受。

Conclusion jiadi combined with bonin plays a remarkable role in improving the qol of patient with terminal osteoid metastasis with few adverse effects , which is good for clinical application .

结论佳迪配合博宁能显著提高晚期恶性肿瘤骨转移患者生活质量，不良反应轻微，值得临床推广。