Ald is caused by a defect in an x chromosome gene that produces a protein called ald .

ald是由x染色体中一个产生ald蛋白质的基因缺陷所引起的。

Then they infused the repaired cells back into the patient , and the cells began cranking out ald protein .

然后把修复的细胞回注患者体内，这些细胞开始快速产生ald蛋白。

In x-linked ald , which strikes mainly boys , patients develop neurological symptoms such as seizures and loss of vision around age 6 to 8 , and within months they become paralyzed , deaf , and eventually die .

连锁ald主要发生于男孩子，患者出现神经系统症状，如大约在6-8岁时癫痫发作和失明，在数个月内瘫痪、耳聋并最终死亡。

But the only widely accepted way to stave off ald is a bone marrow transplant , which is risky -- 20 % to 30 % of patients die or have serious complications -- and works best if the donor marrow comes from a sibling .

但唯一被广泛接受能延缓ald病程的方法是骨髓移植，这一方法的风险患者的死亡率达20%-30%或有严重的并发症而且最好是要移植来自全同胞捐赠的骨髓。

The treatment , in which the virus delivered a therapeutic gene , marks the first time gene therapy has been successfully used against x-linked adrenoleukodystrophy ( ald ) -- a disorder that is always fatal if untreated .

这次治疗中应用的病毒携带的治疗基因，使基因疗法首次成功地应用于抗x-连锁肾上腺脑白质障碍（ald），种如不治疗总是死亡的疾病。