1. 不幸的;可怜的;苦难的
    You describe someone as wretched when you feel sorry for them because they are in an unpleasant situation or have suffered unpleasant experiences.

    e.g. You have built up a huge property empire by buying from wretched people who had to sell or starve.
           你靠从那些不卖房就得挨饿的可怜人手里买下房子后建立起了庞大的房产帝国。

2. 讨厌的;混账的;该死的
    You use wretched to describe someone or something that you dislike or feel angry with.

    e.g. Wretched woman, he thought, why the hell can't she wait?...
           他想，可恶的女人，她怎么就不能等一等呢？
    e.g. Theft is something that really disgusts me. It makes me feel hateful towards this whole wretched island.
           偷窃是让我深恶痛绝的事情，它让我对这整个该死的岛都充满仇视。

3. 苦恼的;难过的;哀伤的
    Someone who feels wretched feels very unhappy.

    e.g. I feel really confused and wretched...
           我觉得十分迷惘，难过极了。
    e.g. The wretched look on the little girl's face made him sorry.
           小女孩脸上痛苦的表情让他很难受。

4. 恶劣的;低劣的
    If you describe something as wretched, you are emphasizing that it is very bad or of very poor quality.

    e.g. What a wretched excuse...
           多么拙劣的借口！
    e.g. The pay has always been wretched.
           薪水总是少得可怜。