1. 庇护；避难
    If you take refuge somewhere, you try to protect yourself from physical harm by going there.

refuge的反义词

    e.g. They took refuge in a bomb shelter...
           他们在防空洞中避难。
    e.g. His home became a place of refuge for the believers.
           他的家成了信徒们的避难之处。

2. 避难所;庇护处;安全地带
    A refuge is a place where you go for safety and protection, for example from violence or from bad weather.

    e.g. ...a refuge for battered women...
           为受到暴力侵害的妇女建的避难所
    e.g. We climbed up a winding track towards a mountain refuge.
           我们沿着一条蜿蜒的小道爬向山上的一处避难所。

3. （行为和想法的）逃避，躲避
    If you take refuge in a particular way of behaving or thinking, you try to protect yourself from unhappiness or unpleasantness by behaving or thinking in that way.

    e.g. All too often, they get bored, and seek refuge in drink and drugs...
           太多的时候，他们觉得无聊就在酒精和毒品中寻求慰藉。
    e.g. Father Rowan took refuge in silence.
           罗恩神父以沉默来逃避。