1. 摆布，操纵，控制(他人)
    If you say that someone manipulates people, you disapprove of them because they skilfully force or persuade people to do what they want.

    e.g. He is a very difficult character. He manipulates people...
           他是个极难对付的角色，总是把人玩弄于股掌之间。
    e.g. She's always borrowing my clothes and manipulating me to give her vast sums of money...
           她老是向我借衣服，还千方百计地要我给她大笔大笔的钱。

2. 摆布，操纵，处理(事件或局势)
    If you say that someone manipulates an event or situation, you disapprove of them because they use or control it for their own benefit, or cause it to develop in the way they want.

    e.g. She was unable, for once, to control and manipulate events...
           她仅有一次没能控制和处理好局势。
    e.g. They felt he had been cowardly in manipulating the system to avoid the draft.
           他们觉得他太没种，居然钻漏洞逃避服役。

3. 操作; 使用
    If you manipulate something that requires skill, such as a complicated piece of equipment or a difficult idea, you operate it or process it.

    e.g. The technology uses a pen to manipulate a computer...
           这项技术使用一支笔来操作电脑。
    e.g. The puppets are expertly manipulated by Liz Walker...
           利兹·沃克熟练地操纵着木偶。

4. 使脱臼复位;用推拿术治疗
    If someone manipulates your bones or muscles, they skilfully move and press them with their hands in order to push the bones into their correct position or make the muscles less stiff.

    e.g. The way he can manipulate my leg has helped my arthritis so much.
           他为我的腿实施的推拿术治疗对我的关节炎大有好处。